New Clinical Trial Recruiting for Myelofibrosis Patients in Spain

The Global MPN Scientific Foundation announces a new clinical trial for individuals with myelofibrosis (MF) in Spain. Clinical trials are the best way to discover new treatments for MF and see how they work in humans.

The company behind this clinical trial is Bristol Myers Squibb (BMS), a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients overcome serious diseases.

The trial, CA011-023, aims to assess the safety and tolerability of a promising oral medication, BMS-986158, in combination with ruxolitinib or fedratinib. The study is recruiting participants with intermediate or high-risk MF, and it’s in phase 1/2.

The primary objective of the trial is to determine the maximum tolerated dose of BMS-986158 when used in combination with ruxolitinib for previously untreated MF patients (1st Line) and in combination with fedratinib for MF patients with prior experience with ruxolitinib (2nd Line).

What makes you an eligible individual for the clinical trial? (Download in PDF)

Inclusion criteria:

• Diagnosis of primary myelofibrosis (PMF), post-essential thrombocythemia (ET) or post-polycythemia vera (PV) myelofibrosis

• Treatment-related toxicities of pretreatment resolved to Grade 1 or pretreatment baseline or determined to be irreversible prior to study treatment

• You must agree to follow specific contraceptive methods, if applicable

• Being over 18 years

Exclusion criteria:

• Pregnant or lactating women in the selection

• Any significant acute or uncontrolled chronic medical illness

• Other inclusion/exclusion criteria defined in the protocol apply

For more information about participating in the Bristol-Myers Squibb clinical trial, visit www.BMSStudyConnect.com. To learn more about this clinical trial and find participating centers in Spain, please visit: https://www.bmsstudyconnect.com/es/es/clinical-trials/NCT04817007.html. Additional information can also be found on the Clinicaltrials.gov website and the Spanish Clinical Trials Registry.

At the Global MPN Scientific Foundation, we strive to provide the latest updates and opportunities for patients with MPNs. Stay informed and take an active role in your healthcare journey!