Myelofibrosis (MF)?

Myelofibrosis is a rare disease affecting blood cell production in the bone marrow. The bone marrow fills with fibrous and scar tissue that prevents the normal function of the stem cells. This causes anemia, neutropenia, and thrombocytopenia, low levels of red blood cells, white blood cells, and platelets. These problems can cause symptoms such as tiredness, infections, bleeding, and bruising.

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Myelofibrosis usually affects people over 60, with no differences between men and women. Its exact frequency is unknown, but it is believed that it can affect between 0.5 and 1.5 people per 100,000 inhabitants.